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Semen may worsen cervical and uterine cancer4 September 2006 A hormone-like molecule found in semen could worsen cervical and uterine (womb) cancer, research has suggested. Experts at the Medical Research Council's Human Reproductive Sciences Unit found that prostaglandins present in semen can enhance tumour growth. Prostaglandins are naturally produced by lining of the female reproductive organs. They regulate cell growth and trigger the womb to either thicken or shed during the menstrual cycle. But the researchers found that concentrations of prostaglandins in semen are up to 1,000 times higher than those normally found in these cells. Dr Henry Jabbour, lead researcher, said that the research "highlights the potential for a new therapeutic approach that will tackle both possible sources of prostaglandin, those produced naturally by women and those introduced to the body by sperm." A cervical screening programme in the UK helps detect changes in the cells of the cervix at a pre-cancerous stage. The Department of Health (DoH) advises that women have their first screening test at 25 and then every three years until they are 49 and five yearly until they are 64. The greatest risk factor for cervical cancer is failing to go for regular screening tests. More information
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