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Caffeine link to miscarriage strengthened
24 January 2008
| Key facts |
- One mug of coffee contains about 100 mg of caffeine in it.
- One cup of tea contains about 50 mg of caffeine in it.
- One 50 g bar of chocolate contains about 50 mg caffeine.
- One can of cola contains about 40 mg caffeine.
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This research provides clearer and stronger evidence that high doses of caffeine intake during pregnancy can increase the risk of miscarriage. 
Dr De-Kun Li, Kaiser Permanente Division of Research, Oakland, California US
Drinking caffeine can raise the risk of miscarriage in the earlier stages of pregnancy, US research indicates.
The study, published in the American Journal of Obstetrics and Gynecology, suggests that consuming over 200mg of caffeine a day - about two mugs' worth of coffee - during the first 20 weeks of pregnancy doubles the rate of early pregnancy loss.
"This research provides clearer and stronger evidence that high doses of caffeine intake during pregnancy can increase the risk of miscarriage," explained lead researcher Dr De-Kun Li.
"The main message for pregnant women from these findings is that they probably should consider stopping caffeine consumption during pregnancy," he added.
For the study, Li and colleagues examined the effects of caffeine in 1063 pregnant women during the first 20 weeks of pregnancy. They found that any source of caffeine, not just coffee, appeared to raise the risk of miscarriage.
A link between drinking caffeine while pregnant and low birth weight and miscarriage has previously been suspected, but this is the first study to take into account levels of morning sickness. This could reduce how much caffeine a woman drinks.
The Food Standards Agency (FSA) currently advises pregnant women not to drink more than 300mg of caffeine a day (the equivalent of six cups of tea, or three mugs of coffee). This was based on the Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment evaluation on the reproductive effects of caffeine.
A spokesperson from the FSA told the health information team: "In order to provide a more robust basis for the FSA's advice to pregnant women on caffeine consumption, an FSA-funded study, involving around 2500 pregnant women, was commissioned in 2003."
"This is almost complete and the results will be presented to the Committee On Toxicity in closed session for consideration. We will ask the Committee to also look at this new American study."
The spokesperson added: "When the Committee has reached conclusions the Agency will, if appropriate, revise its advice on caffeine consumption in pregnancy."
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