25 February 2005 (updated 18 October 2005) - written by Bupa's health information team
A number of Asian countries have been affected by avian flu (bird flu) infecting their poultry stocks. In some of these countries, a small number of people have caught the bird flu virus from chickens.1
Scientists fear that the bird flu virus could merge with a human flu virus. This might result in a new, fatal flu virus that could be passed rapidly from person to person with potentially devastating results.
To keep the outbreak of bird flu virus under control, many of the Asian countries are culling their poultry stocks to prevent further spread of the virus.
Avian refers to birds and flu is the common name for influenza. Avian flu is influenza that infects birds, including wild birds such as ducks and domestic birds such as chickens. Avian flu is caused by influenza virus type A. There are 15 subtypes influenza A, two of which affect birds. These are called the H5 and the H7 subtypes.1
These viruses are known as "highly pathogenic (disease-causing) avian influenza" (HPAI). They produce a severe disease in birds and are rapidly fatal, leading to bird flu epidemics.
One such bird flu virus (the H5N1 subtype) is currently infecting chickens in Asian countries.
The bird flu virus can occasionally jump between species and infect people who have been in close contact with infected birds.1
Most people who catch bird flu become very ill or die. As of 28th January 2005, 55 people in Asia have been infected with bird flu and 42 of these people have died.2
When a bird is infected with bird flu, it sheds the flu virus in its faeces, saliva and mucus. Other birds become infected by eating or inhaling the virus.
The virus can infect people who are in close contact with infected birds - for example by people inhaling dried faeces that have become trampled into dust or stuck to the feathers or other parts of the body of the infected bird.1
People cannot catch bird flu from eating cooked chickens.
The ability of bird flu viruses to infect humans throws up this worrying possibility. A bird flu virus could merge with a human flu virus to create a new virus. This new virus could then be passed between humans. If this happens with a highly pathogenic avian influenza virus, the result could be a pandemic of highly contagious flu.
When a new, highly infectious form of a flu virus is formed it can rapidly infect a large number of people. The result is an illness that rapidly spreads round the world and may cause widespread loss of life. An example is the Spanish flu pandemic of 1918-1919 which caused an estimated 40-50 million deaths worldwide.3
There are two ways in which a bird flu virus could merge with a human flu virus, creating a new virus that can be easily passed between humans:
In humans - if a person who already has flu comes into close contact with birds who have highly pathogenic bird flu, there is a tiny chance that the person could become infected with the bird flu virus. If this happens, the person would now be carrying both the human flu virus and the bird flu virus. The two viruses could meet in the person's body and swap genes with each other.3
In pigs - pigs are susceptible to both human and bird flu viruses. If a pig became infected with both viruses at the same time, it could act as a "mixing vessel", allowing the two viruses to swap genes and produce a new virus.
There are signs that it might have been. It seems to have been passed between a child and her mother in Thailand, and in a family in Vietnam.2
However, so far there has been no sustained human-to-human transmission ie it has not spread any further than between close family.2
No. Scientists have not discovered an influenza type a (H5N1) virus that contains both human and bird virus genes. This means that the bird flu virus has not merged with the human flu virus.2
These isolated cases of person to person transmission may have been caused by the basic bird virus being passed on due to close contact.4
Human flu symptoms are:
Cases of bird flu are more likely to cause breathing problems and pneumonia, and can be fatal.
Antiviral medications used to treat human flu viruses help to reduce the symptoms of bird flu, but it's not yet clear whether these work for the current type of bird flu.1
There is currently no vaccine to prevent bird flu in humans. Currently available vaccines are not effective against the H5N1 strain of the virus. Scientists are working on developing a vaccine, but it is difficult because the virus frequently changes.1
As of February 23rd 2005, countries affected by bird flu include Cambodia, China, Hong Kong, Indonesia, Japan, Korea, Laos, Malaysia, Thailand and Vietnam.5
The advice for travellers to these countries is to avoid places where live poultry are raised or kept, such as poultry farms and bird markets, and to avoid contact with sick or dead poultry.
Travellers are also advised to make sure that chicken eaten in affected countries is cooked thoroughly.1
The advice for residents of these countries is the same as the advice for travellers (see above).
In the countries that have been affected by bird flu, governments have begun to cull affected poultry stocks. By removing the potential for the virus to spread through the countries' chicken populations, it is hoped that the virus will be contained and removed from circulation.
All websites accessed on 23 February 2005