Cookies on the Bupa website

We use cookies to help us understand ease of use and relevance of content. This ensures that we can give you the best experience on our website. If you continue, we'll assume that you are happy to receive cookies for this purpose. Find out more about cookies

Continue

Alzheimer's disease

Alzheimer's disease is a form of dementia, which gradually damages the way your brain works. It can affect your memory, your ability to communicate and to make decisions, and your ability to carry out daily activities. The disease develops slowly, usually over many years.

Alzheimer's disease is the most common cause of dementia, affecting nearly 500,000 people in the UK. Dementia is the medical term used to describe a number of conditions that cause a change in the way your brain works. These changes can cause memory problems and can alter your behaviour and emotions. You may also have problems making decisions and solving problems, or be unable to carry out your usual daily activities, such as driving, getting dressed or eating. The effects of dementia are different for each individual.

Alzheimer's disease changes the structure of your brain and causes your brain cells to die. It also affects the chemicals that are responsible for transmitting signals between your brain cells, which means that nerve messages aren't passed on properly. Over time, as more and more areas of your brain become damaged, your symptoms will get progressively worse.

Most people who develop the condition are over 65, although it can also develop in younger people. If you have Alzheimer's disease, you will usually live with the illness for several years, but this depends on when you’re diagnosed.

Read more Close
Early signs of dementia
Professor Graham Stokes

Details

  • Symptoms Symptoms of Alzheimer's disease

    Alzheimer's disease is a condition that develops over many years. The symptoms get progressively worse over time. If you develop Alzheimer's disease before you're 65 (early-onset), your symptoms may get worse more rapidly than in people who develop it later.

    One of the first symptoms of Alzheimer's disease is forgetfulness – for example, forgetting the name of an acquaintance or forgetting where you have put something. However, this isn't always caused by dementia and may just be a sign of getting older or simply the stress of a busy life. You might also have trouble finding the right words when talking or writing.

    As Alzheimer's disease develops, you, or your family or friends, may notice other symptoms. Alzheimer's disease affects everyone differently. You may have some but not all of the symptoms listed below.

    • You may become confused or disorientated – for example, you may not know what time of day it is, feel bemused and believe you're somewhere you're not, or you may not recognise familiar places or people.
    • You may feel irritable, become less interested in life, or become depressed or anxious.
    • You may have problems doing everyday tasks, such as preparing a meal, laying the table, getting dressed, shopping or dealing with money.
    • You may take less care of yourself, for example, not washing regularly or eating properly.
    • Communicating may become more difficult. You may struggle to complete sentences or understand all of what is being said to you. You may also have difficulty finding the words you need.

    If you start to notice these symptoms, see your GP.

    During the later stages of the disease, you're likely to be frail and increasingly dependent on other people. In general, your memory loss will get worse, and you may not recognise your close family or your partner. Eventually, you will become dependent on others to care for you.

    The symptoms of Alzheimer's disease can cause a great deal of distress and upset for you, and your carers and family, who may feel they have lost the person they once knew.

  • Diagnosis Diagnosis of Alzheimer's disease

    Alzheimer's disease can be difficult to diagnose, especially in the early stages.

    Your GP may ask you a series of questions designed to test your memory and thinking, for example, using a test called the Mini-Mental State Examination. He or she may also ask you to have a urine test or blood tests to see whether any other condition may be causing your symptoms, which may be treatable.

    If your GP thinks that you may have Alzheimer's disease, he or she is likely to refer you to a Memory Assessment Service to see specialist doctors and nurses for more tests. These may include further tests to check your memory and thinking, and observation of your behaviour. You may be asked to have a CT or MRI brain scan.

  • Treatment Treatment options for Alzheimer's disease

    There are a number of treatment options for Alzheimer’s disease, as described below. Treatments for Alzheimer's disease can't cure the condition but, for some people, they may slow down the development of the disease for a period of time. Which treatments you are offered will depend on your personal circumstances. Your doctor will discuss these with you to help you make a decision that’s right for you. Your decision will be based on your doctor’s expert opinion and your own personal values and preferences.

    Medicines

    People with Alzheimer's disease don’t have enough of a chemical called acetylcholine in their brain. Acetylcholine helps nerve signals to travel across the gaps (synapses) between nerve cells (neurones). Medicines called acetylcholinesterase inhibitors can help to stop the level of acetylcholine in your brain falling any further. There are three acetylcholinesterase inhibitors available: donepezil hydrochloride, rivastigmine and galantamine. 

    Your doctor may offer you these medicines if you have mild or moderately-severe Alzheimer's disease, because they can help slow down the development of symptoms for a while. However, they are unlikely to extend your lifespan.

    If you have late-stage Alzheimer's disease, your doctor may give you the option of taking a medicine called memantine. This works in a different way to acetylcholinesterase inhibitors. It may help to improve your thinking and memory and allow you to do more basic everyday activities such as washing.

    Your doctor may also offer you medicines to help treat some of the symptoms of Alzheimer's disease, such as anxiety, sleep disturbance or irritability. He or she will discuss the potential benefits and side-effects of these medicines with you. If you also have depression, your doctor may offer you antidepressants to treat it.

    Talking therapies

    Your doctor may suggest other treatments that can help you to deal with memory loss, emotional symptoms and changes in your behaviour. Some of the main ones are listed below.

    • Cognitive stimulation therapy. This uses memory and reasoning exercises, as well as reminiscence and multisensory stimulation to improve your ability to learn, remember and think. The programme helps with memory problems, day-to-day activities and reality orientation.
    • Multisensory stimulation. This can help to improve your quality of life and includes music and pet therapy, aromatherapy and massage.
    • Psychological interventions can help to reduce problems such as anger, agitation and depression.
    • Meaningful activities and engagement such as having conversations, ‘life story’ work (focusing on the person’s past), painting and drawing, cooking and games. These can help you to express yourself and improve your quality of life and sense of wellbeing.
  • Bupa Care Homes

    At a Bupa care home, our dedicated staff look after the individual needs of our residents while giving them as much independence as possible.

  • Causes Causes of Alzheimer's disease

    Doctors don't know exactly why some people develop Alzheimer's disease, but it's associated with a number of risk factors. These may include:

    • ageing – Alzheimer's disease mainly affects older people two-thirds of people who have Alzheimer’s disease are over 80 years old
    • genetics – you may be more likely to develop Alzheimer's disease if your parents or a close relative has it
    • a previous severe head injury
    • lifestyle factors, such as smoking or obesity
    • diabetes
    • raised blood pressure and raised blood cholesterol levels

    If you have Down's syndrome, you are also at greater risk of developing Alzheimer's disease as you get older.

  • Complications Complications of Alzheimer's disease

    As Alzheimer's disease progresses, you will become less mobile and less able to carry out your usual activities. You may be more likely to develop infections, such as pneumonia and bladder infections. Having Alzheimer's disease means it can be difficult to deal with these kinds of infections and illnesses, which can make it harder to recover.

    Many people who have Alzheimer's disease live for years with the condition. When people die from Alzheimer's disease, it's normally due to a related problem, such as an infection, rather than the disease itself. However, Alzheimer's disease can also be fatal itself if it progresses to the point where the areas of your brain that control essential functions, such as breathing, swallowing and balance, are affected.

  • Help and support Help and support

    If you have Alzheimer's disease, you may be looked after at home, in a care home or sometimes in hospital. The people who care for you can help you to look after yourself and stay healthy and safe.

    If you're looking after someone with Alzheimer's disease at home, you're likely to need extra help and support. Looking after someone with dementia can be stressful and sometimes carers can neglect their own health and wellbeing.

    As a carer, it's important to take regular breaks so that you can look after yourself and take some time to relax. Respite care is when someone comes into your home to care for the person with dementia while you take a break, or when the person with dementia attends a day centre or goes into a care home or hospital for a period of time. Organisations such as the Alzheimer's Society and Carers UK can give you more information about respite care.

  • Prevention Prevention of Alzheimer's disease

    There are many risk factors for Alzheimer’s disease but as yet no definite ways to help prevent you developing it. There’s nothing you can do about your genes or your age, but aiming to live a healthy lifestyle may give you some protection. It has been found that the same risk factors for cardiovascular disease can increase your risk of Alzheimer’s disease. By making certain healthy lifestyle changes, you may be protecting yourself against both diseases. Try to do the following to stay healthy.

    • Exercise regularly – it’s recommended that you do 150 minutes a week in bouts of 10 minutes or more.
    • Don’t smoke.
    • Maintain a healthy weight.
    • Take measures to control high blood pressure or high cholesterol if you have it.
    • Control your blood glucose if you have diabetes.
    • Eat a healthy, balanced diet with lots of fruit and vegetables and low amounts of saturated fat.

    As well as making lifestyle changes, some studies suggest that trying to keep as active as possible, with lots of interests and hobbies might help prevent Alzheimer’s disease. Other researchers have found that spending more time in education may also help to lower your risk.

    It’s not yet known whether eating oily fish or taking B vitamins can reduce the risk of Alzheimer’s disease because studies so far have had mixed results.

  • FAQs FAQs

    I have been diagnosed with mild cognitive impairment. Does this mean I will develop Alzheimer's disease?

    Answer

    No, a diagnosis of mild cognitive impairment doesn't mean that you will necessarily develop Alzheimer's disease.

    Explanation

    Mild cognitive impairment is a term used by doctors to describe age-related exaggerated absent-mindedness. If you have this, it means you have some problems with your memory, but it doesn’t mean that you have dementia.

    Mild cognitive impairment isn't a specific medical condition or disease. People with it don’t usually have any other signs or symptoms of dementia. It's very common to have memory problems, particularly as you get older, and most people will have this at some time in their lives.

    There can be a number of reasons why you may have developed memory problems. With age, memory becomes more inefficient. However, exaggerated forgetfulness can also be caused by stress, anxiety, depression or a physical illness. It's important to see your GP if you have memory problems.

    Although many people with mild cognitive impairment find their memory improves or remains stable and they don't go on to develop dementia, for some it can be an early symptom of Alzheimer's disease.

    There aren't any tests to find out the cause of mild cognitive impairment or to tell if it will lead to Alzheimer's disease or another type of dementia. Talk to your GP if you're worried about mild cognitive impairment and Alzheimer's disease.

    Does aluminium cause Alzheimer's disease?

    Answer

    Doctor's don't yet know exactly what causes Alzheimer's disease, but it's thought to be a combination of factors. At the moment, there is no direct evidence to show that aluminium causes the condition.

    Explanation

    Aluminium is a metal found in some of the foods we eat and in drinking water. It's also used to make packaging, cooking pots and pans, and some medicines. The aluminium that you eat or drink passes through your body and very little of it is taken in.

    During the 1960s and 1970s researchers discovered a possible link between aluminium and Alzheimer's disease. Since then, more research has been done that found some links but hasn't shown that aluminium causes dementia. It's difficult for researchers to be more sure of the effects of aluminium because Alzheimer's disease is a common condition that has many causes, and because aluminium is found in many places in our environment.

    Can Ginkgo biloba help to treat Alzheimer’s disease?

    Answer

    Ginkgo biloba is a herbal remedy traditionally used to improve memory. The results of research on the effects of taking Ginkgo biloba to treat Alzheimer's disease are uncertain. Some research shows that it may help to improve symptoms whereas other research shows no effects.

    Explanation

    Ginkgo biloba comes from the maidenhair tree and has been used in traditional Chinese medicines for many years. A number of research trials have looked at whether or not Ginkgo biloba may be able to treat dementia. The results of this research have been mixed, some showing that it may help to improve symptoms and other research showing no effect. A study published in the Journal of the American Medical Association found that Ginkgo biloba was no better than a placebo (dummy pill) for preventing cognitive decline in older adults.

    Ginkgo biloba can cause bleeding if you take it with warfarin or aspirin and it may also cause health problems if mixed with some other medicines. Don’t start taking any herbal remedies without speaking to your GP or pharmacist first.

  • Resources Resources

    Further information

    Sources

    • What is Alzheimer's disease? Alzheimer's Society. www.alzheimers.org.uk, published April 2011
    • About dementia. Alzheimer's Society. www.alzheimers.org.uk, accessed 3 January 2013
    • Burns A, Iliffe S. Alzheimer’s disease. BMJ 2009; 338:b158. doi:10.1136/bmj.b158
    • Alzheimer’s disease – early-onset Alzheimer's. Alzheimer's Research UK. www.alzheimersresearchuk.org, published March 2012
    • Alzheimer's dementia. BMJ Best Practice. www.bestpractice.bmj.com, published 3 October 2011
    • Grief and bereavement. Alzheimer's Society. www.alzheimers.org.uk, published November 2010
    • The later stages of dementia. Alzheimer's Society. www.alzheimers.org.uk, published March 2012
    • Hughes J, Lloyd-Williams M, Sachs G. Supportive care for the person with dementia. 1st ed. Oxford: Oxford University Press, 2010:21–26
    • Dementia UK: the full report. Alzheimer's Society, 2007. www.alzheimers.org.uk
    • Dementia – assessment. Map of Medicine. www.mapofmedicine.com, published 31 January 2012
    • Diagnosis and assessment. Alzheimer's Society. www.alzheimers.org.uk, published February 2011
    • Joint Formulary Committee. British National Formulary (online) London: BMJ group and Pharmaceutical Press. www.medicinescomplete.com, accessed 3 January 2013
    • Treatments. Alzheimer's Research UK. www.alzheimersresearchuk.org, published April 2012
    • Woods B, Aguirre E, Spector A, et al. Cognitive stimulation to improve cognitive functioning in people with dementia. Cochrane Database of Systematic Reviews 2012, Issue 2. doi:10.1002/14651858.CD005562.pub2
    • Dementia: Supporting people with dementia and their carers in health and social care. National Institute for Health and Care Excellence (NICE). November 2006. www.nice.org.uk
    • Psychological treatments for people with dementia who have behavioural symptoms. Alzheimer's Society. www.alzheimers.org.uk, accessed 5 March 2013
    • Management of patients with dementia. Scottish Intercollegiate Guidelines Network (SIGN), February 2006. www.sign.ac.uk
    • Respite care. Alzheimer's Society. www.alzheimers.org.uk, published September 2011
    • Risk factors and prevention. Alzheimer's Research UK. www.alzheimersresearchuk.org, published November 2012
    • Brayne C, Ince P, Keage H, et al. Education, the brain and dementia: neuroprotection or compensation? Brain 2010; 133(8):2210–16. doi:10.1093/brain/awq185
    • Dementia – background information. NICE Clinical Knowledge Summaries, www.cks.nice.org.uk, published March 2010
    • Mild cognitive impairment. Alzheimer's Society. www.alzheimers.org.uk, published March 2012
    • Aluminium and Alzheimer's disease. Alzheimer's Society. www.alzheimers.org.uk, published September 2008
    • Herbs at a glance: ginkgo. National Center for Complementary and Alternative Medicine. www.nccam.nih.gov, published April 2012
    • Snitz B, O'Meara E, Carlson M, et al. Ginkgo biloba for preventing cognitive decline in older adults. JAMA 2009; 302(24):2663–70. doi:10.1001/jama.2009.1913
  • Related information Related information

  • Author information Author information

    Produced by Pippa Coulter, Bupa Health Information Team, May 2013.  

    We welcome your feedback on this topic
    Submit an FAQ on this topic

About our health information

At Bupa we produce a wealth of free health information for you and your family. We believe that trustworthy information is essential in helping you make better decisions about your health and care. Here are just a few of the ways in which our core editorial principles have been recognised.

  • Information Standard

    We are certified by the Information Standard. This quality mark identifies reliable, trustworthy producers and sources of health information.
    Information standard logo
  • HONcode

    We comply with the HONcode for trustworthy health information: verify here
    HON code logo
  • Plain English Campaign

    We hold the Crystal Mark, which is the seal of approval from the Plain English Campaign for clear and concise information.
    Plain English Campaign logo

Our core principles

All our health content is produced in line with our core editorial principles – readable, reliable, relevant – which are represented by our diagram.

An image showing or editorial principals

                  Click to open full-size image

The ‘3Rs’ encompass everything we believe good health information should be. From tweets to in-depth reports, videos to quizzes, every piece of content we produce has these as its foundation.

Readable

In a nutshell, our information is jargon-free, concise and accessible. We know our audience and we meet their health information needs, helping them to take the next step in their health and wellbeing journey.

Reliable

We use the best quality and most up-to-date evidence to produce our information. Our process is transparent and validated by experts – both our users and medical specialists.

Relevant

We know that our users want the right information at the right time, in the way that suits them. So we review our content at least every three years to keep it fresh. And we’re embracing new technology and social media so they can get it whenever and wherever they choose.

Our accreditation

Don’t just take our word for it. Here are just a few of the ways in which the quality of our information has been recognised.

  • The Information Standard certification scheme

    You will see the Information Standard quality mark on our content. This is a certification programme, supported by NHS England, that was developed to ensure that public-facing health and care information is created to a set of best practice principles.

    It uses only recognised evidence sources and presents the information in a clear and balanced way. The Information Standard quality mark is a quick and easy way for you to identify reliable and trustworthy producers and sources of information.

    Certified by the Information Standard as a quality provider of health and social care information.

  • HONcode

    We comply with the HONcode (Health on the Net) for trustworthy health information. Certified by the HONcode for trustworthy health information.

  • Plain English Campaign

    Our website is approved by the Plain English Campaign and carries their Crystal Mark for clear information. In 2010, we won the award for best website.

    Website approved by Plain English Campaign.

  • British Medical Association (BMA) patient information awards

    We have received a number of BMA awards for different assets over the years. Most recently, in 2013, we received a 'commended' award for our online shared decision making hub.

Contact us

If you have any feedback on our health information, we would love to hear from you. Please contact us via email: healthinfo@bupa.com. Or you can write to us:

Health Content Team
Bupa House
15-19 Bloomsbury Way
London
WC1A 2BA

Find out more Close

Legal Disclaimer

This information was published by Bupa's Health Information Team and is based on reputable sources of medical evidence. It has been reviewed by appropriate medical or clinical professionals. Photos are only for illustrative purposes and do not reflect every presentation of a condition. The content is intended only for general information and does not replace the need for personal advice from a qualified health professional. For more details on how we produce our content and its sources, visit the about our health information page.

^ Calls may be recorded and may be monitored.